In the first meeting between these two teams in 2020, the Wigan Warriors featured six debutants including Kai Pearce-Paul and Umlya Hanley to face St Helens.
With both sides playing each other in the Challenge Cup semi-final on final, the Salford Red Devils and Warrington Wolves rotated their sides in their round 13 tie.
The Wests Tigers waved goodbye to Benji Marshall and Chris Lawrence as they faced the Parramatta Eels at Bankwest Stadium, with the Eels looking to lock in a top-four spot.
In a potential pre-cursor to the opening match in the finals, the Cronulla Sharks welcomed Canberra Raiders to Netstrata Jubilee Stadium to round off the regular season for both sides.
The Penrith Panthers looked to end the regular season, with a 15th win on the bounce as they travelled to face the Canterbury Bulldogs.
The Wigan Warriors and Wakefield Trinity faced off at the Halliwell Jones Stadium as they wrapped up round 13, with a tough clash in the rain.
South Sydney Rabbitohs and the Sydney Roosters clashed for the final time in the 2020 regular season, with the Rabbitohs needing a win for a home tie next week.
The Gold Coast Titans looked to equal a club record of five consecutive wins, as they welcomed the Newcastle Knights to Cbus Stadium for the last round in 2020.