In a late rearranged fixture, Hull FC faced the Leeds Rhinos at Headingley, after the withdrawal from Castleford Tigers after multiple positive COVID-19 tests.
Super League returned after the weekend break, with Challenge Cup Finalists Salford Red Devils travelling to West Yorkshire to face a Huddersfield Giants side unbeaten under Luke Robinson.
The Castleford Tigers returned to The Mend-a-Hose Jungle, as they welcomed a Hull FC side looking to finish as high up the Super League table as possible.
In the first meeting between these two teams in 2020, the Wigan Warriors featured six debutants including Kai Pearce-Paul and Umlya Hanley to face St Helens.
With both sides playing each other in the Challenge Cup semi-final on final, the Salford Red Devils and Warrington Wolves rotated their sides in their round 13 tie.
The Wigan Warriors and Wakefield Trinity faced off at the Halliwell Jones Stadium as they wrapped up round 13, with a tough clash in the rain.
The Huddersfield Giants, fresh off the exit of Simon Woolford, travelled to face a inconsistent Wakefield Trinity side looking to move towards the top-eight.
Rugby League fans will return to the Betfred Super League in England on Wednesday, September 30 after the Government granted permission for four fixtures to be staged as pilot events.