St George Illawarra and South Sydney battled as top eight outsiders after round 11 defeats delivered significant setbacks to their 2020 finals hopes.
In a battle between sixth and ninth, the Canberra Raiders welcomed the South Sydney Rabbitohs to GIO Stadium as both sides looked to sit more comfortably in the top-eight.
Newcastle Knights travelled to face a much more consistent South Sydney Rabbitohs side, as they looked to hop off their roller-coaster ride at Bankwest Stadium.
In a battle between eighth and ninth, the South Sydney Rabbitohs face Wests Tigers at Bankwest Stadium, with the victor sitting a little more comfortably in the top-eight.
The Canterbury Bulldogs, at the foot of the ladder, welcomed a South Sydney Rabbitohs side looking to bounce back from a disappointing defeat last weekend.
Penrith and South Sydney clashed at Netsrata Jubilee Stadium on Thursday, as the Rabbitohs looked to solidify their position in the top-eight, and the Panthers looking to go top.
With the New Zealand Warriors stunning the Cowboys last weekend, the South Sydney Rabbitohs would have to be wary of their opponents as they clashed at Bankwest Stadium.
After breaking an almost year-long win drought, the Gold Coast Titans travelled to NSW to meet a South Sydney Rabbitohs team also sitting on a 1-3 record.