The Brisbane Broncos faced a tough task turning around their nightmare season against an in-form Cronulla Sharks side looking to get into the top four conversation, after five wins from their last six.
The St George Illawarra Dragons faced the Cronulla Sharks at the Netstrata Jubilee Stadium in a derby that would have different final implications depending on the result.
The New Zealand Warriors faced the Cronulla Sharks at the Central Coast Stadium with both sides looking to bounce back from defeats in round nine.
The Cronulla Sharks were quietly working themselves back into finals contention, but they faced a tough test against the Penrith Panthers who were sitting pretty in the second.
The Gold Coast Titans welcomed Cronulla Sharks to Cbus Super Stadium, as both sides looked to build on the back of impressive wins last round.
With the Steve Rogers Memorial Trophy up for grabs, Cronulla Sharks travelled to face a Manly Sea Eagles side without Tom Trbojevic in the hope of moving up the ladder.
With just one win each, both the Cronulla Sharks and Canterbury Bulldogs needed a win to move away from the bottom of the ladder, and one of them would as they clashed as Bankwest Stadium.
After the kick-off time was brought forwards, the winless St George Illawarra Dragons faced local rivals Cronulla Sharks at Campbelltown Stadium as both teams looked to save their season.